منابع مشابه
Pulmonary Drug Delivery
Growing attention has been given to the potential of a pulmonary route as an noninvasive administration for systemic delivery of therapeutic agents (mainly peptides and proteins) due to the fact that the lungs could provide a large absorptive surface area (up to 100 m ) but extremely thin (0.1 μm – 0.2 μm) absorptive mucosal membrane and good blood supply. However, recent advances show great pr...
متن کاملPulmonary Drug Delivery System
Pulmonary drug delivery is primarily use to treat conditions of the airways, delivering locally acting drugs directly to their site of action. These routes of drug delivery may give the advantages like small amount of drug, less adverse reaction and rapid onset of action. The human respiratory system is complicated organ system these system consist of two reagions conducting airways and respira...
متن کاملLarge porous particles for pulmonary drug delivery.
A new type of inhalation aerosol, characterized by particles of small mass density and large size, permitted the highly efficient delivery of inhaled therapeutics into the systemic circulation. Particles with mass densities less than 0.4 gram per cubic centimeter and mean diameters exceeding 5 micrometers were inspired deep into the lungs and escaped the lungs' natural clearance mechanisms unti...
متن کاملUltrasonic nebulization platforms for pulmonary drug delivery.
IMPORTANCE OF THE FIELD Since the 1950s, ultrasonic nebulizers have played an important role in pulmonary drug delivery. As the process in which aerosol droplets are generated is independent and does not require breath-actuation, ultrasonic nebulizers, in principle, offer the potential for instantaneously fine-tuning the dose administered to the specific requirements of a patient, taking into a...
متن کاملDry powder inhalers for pulmonary drug delivery.
The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery. However, they are also complicated systems, the the performa...
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ژورنال
عنوان ژورنال: Therapeutic Delivery
سال: 2013
ISSN: 2041-5990,2041-6008
DOI: 10.4155/tde.13.89